Knox made a brief statement after Italy's Supreme Court overturned her murder conviction late Friday.
She was prosecuted after the semi-naked body of British student Meredith Kercher, 21, her throat slashed, was found in November 2007 in the apartment the two women shared.
Raffaele Sollecito, Knox's Italian boyfriend, was convicted as well. He was cleared along with Knox on Friday night.
"She was my friend ... she deserved so much better," Knox said of Kercher.
Knox had been facing 28½ years in prison. Now she can seek a normal life.
She was in the United States when the decision was announced in Rome and issued a statement, saying she was "relieved and grateful."CLICK HERE TO READ THE ENTIRE STORY AT CNN.COM